Pharmacogenomics (PGx) explores how genes influence an individual's response to medications. It assesses the patient's metabolic profile, potential drug-gene interactions, and drug-drug interactions. Using a simple buccal swab, we analyze germ-line variants that may impact a patient's response to specific drugs. Our testing identifies patient-specific metabolisms for key enzymes, including CYP2D6, CYP2C9, CYP2C19, CYP3A4/3A5, CYP1A2, VKORC1, DPYD, TPMT, UGT1A1, Factor II, Factor V, MTHFR, SLCO1B1, and TYMS.

We identify various drug-gene and drug-drug interactions, including:

• Drugs associated with an increased risk of serotonin syndrome, seizures, QTc prolongation, and anticholinergic effects.
• Potent inhibitors or inducers that may impact the bioavailability of other drugs in the profile.
• Major drug interactions categorized as Category D or X.
• Drugs with a narrow therapeutic window.
• Drugs with Black Box Warnings.

Our organization furnishes practitioners and patients with comprehensive and actionable information. Our reports present specific diagnostic results based on relevant markers acquired through state-of-the-art testing, enabling practitioners to promptly make informed decisions and identify suitable therapies. These reports are designed to be intuitive and easily comprehensible, empowering patients to actively participate in their healthcare. Additionally, our alternative drug assessment for commonly used medications offers valuable insights into drug interactions, side effects, and potential alternatives, aiding practitioners and patients in making informed decisions about their healthcare.

At GreenMCMeds, we understand the importance of comprehensive clinical support for practitioners. That's why we offer ongoing discussions about the clinical implications of initial diagnostics and reports, along with proactive, predictive recommendations to improve diagnosis and optimize therapy decisions. We continuously monitor drug dosages to ensure appropriateness and recommend adjustments when needed. By providing the right tools and support, we enable practitioners to make informed decisions and deliver the best care possible.

Modern prescribers require advanced diagnostic solutions to manage patients effectively. As a leading provider of diagnostic and medical support, we offer medication monitoring to confirm patient compliance, identify potential drug-drug interactions, and detect unauthorized drug use through the latest drug screening technologies. When combined with pharmacogenomics testing, medication monitoring allows for optimized drug dosing, reducing adverse drug reactions and improving patient outcomes.

Our medication monitoring program includes baseline testing for new patients, those starting opioid therapy, patients on long-term or chronic therapy, and random drug testing when appropriate. Confirmatory testing helps identify abnormalities in drug metabolism that can affect treatment outcomes and highlight discrepancies between desired goals and actual patient response.

Today's prescribers require diagnostic solutions that improve the clinical management of patients. GreenMCMeds is a leading diagnostic and medical decision support company dedicated to providing practitioners with medication monitoring. To achieve this, GreenMCMeds uses the latest drug screening technologies that confirm patient compliance with drug regimens, the detection of medication duplications (e.g., opiates), and the detection of illicit drug use. Used in combination with our pharmacogenomics testing, medication monitoring enables the optimization of drug dosing and the minimization of drug interactions.

GreenMCMeds medication monitoring includes:

• Baseline testing for new patients, patients initiating opioid therapy, patients on long-term, chronic therapy, and random drug testing when appropriate and medically necessary.
• Confirmatory testing for positive baseline testing results, revealing abnormalities in drug metabolism and exposing inconsistencies between desired treatment outcomes and the current patient response.
• High-complexity testing with high-performance LC/MS (liquid chromatography/mass spectrometry) techniques to ensure the highest level of sensitivity and specificity.
• Highly accurate, clinically relevant reports are delivered through a secure online portal for rapid results and quick treatment decisions. The credentialed staff of technologists and PharmDs are CLIA-certified, high-complexity lab partners.

We understand the risks to both prescribers and patients associated with medications that are not taken as prescribed. By partnering with GreenMCMeds for medication monitoring, prescribers will receive clinical data that ensures improved patient compliance and outcomes, informed support of treatment decisions for proper and effective medication dosing, and a lowered rate of prescription drug misuse to increase patient safety and mitigate prescriber liability.

Our integrated solution provides a comprehensive view to support practitioners and patients in making informed decisions, utilizing proprietary pharmacogenomics testing (PCx).

Our integrated genomic diagnostics can help you:

• Minimize trial-and-error medicine
• Avoid adverse drug reactions
• Reduce polypharmacy
• Reduce toxicity
• Improve effectiveness of therapy

By utilizing this intuitive pairing, clinical judgment can be dramatically improved, resulting in more accurate, comprehensive, and effective treatment regimens. The ultimate goal is to enhance a patient's life and increase their likelihood of living longer.